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Also, with quality care, there is no difference in outcome whether the client was treated by a psychiatrist versus a primary care physician. The cyclic antidepressants, also referred to as tricyclics, are among the oldest group of antidepressants dating from the 1950s.
Tofranil, Elavil and Anafranil for example, were the preferred treatments from the 1950s to the late 1980s.
Cymbalta and Other SNRIs Add an Extra “Punch” Beyond SSRIs. In 1994, it was marketed as “Prozac with a punch.” The “punch” refers to Effexor’s probable activating effects on norepinephrine at doses of 150mg. At doses of less than 150mg., Effexor behaves like the SSRIs.
The Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) are considered dual-action antidepressants in that they enhance the actions of serotonin and norepinephrine. Effexor has no anticholinergic side effects and is not sedating.
Popular SSRIs Offer Ease of Use but Increase Discontinuation Concerns.
The Selective Serotonin Reuptake Inhibitors (SSRIs) are indeed popular – one of the most famous, Prozac, ending up on the cover of Newsweek magazine.
In 1990, the year when Prozac became the first drug ever to be featured on the cover of a major U. news magazine, a turning point in psychopharmaceutical history was established.